Medicine

Progressing ASO therapies from growth to application

.Completing interests.R.S., M.S., H.G. as well as A.A.R. are organizers of the 1M1M campaign. H.G. and A.A.R. are board of supervisors participants and also R.S., M.S. and A.A.R. are actually participants of the medical advising committee of N1C. A.A.R. reveals job through LUMC, which has patents on exon-skipping innovation, some of which has actually been licensed to BioMarin as well as consequently sublicensed to Sarepta. As co-inventor of some of these licenses, A.A.R. was actually entitled to a portion of aristocracies. A.A.R. better reveals serving as specialist for PTC Therapeutics, Sarepta Therapeutics, Regenxbio, Dyne Therapies, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and also Astra Zeneca. Previously 5 years, A.A.R. also carried out impromptu seeking advice from for Alpha Anomeric. A.A.R. also discloses registration of the clinical advisory boards of Eisai, Hybridize Therapeutics, Muteness Therapies, Sarepta Therapies, Sapreme and Mitorx. Previously 5 years, A.A.R. was actually likewise a clinical advisory board participant for ProQR. Wage for A.A.R. u00e2 s consulting and also encouraging tasks is actually paid to LUMC. Before 5 years, LUMC also received audio speaker gratuity from PTC Rehabs, Alnylam Netherlands, Italfarmaco as well as Pfizer as well as moneying for agreement analysis coming from Sapreme, Eisai, Galapagos, Synaffix and Alpha Anomeric. Task backing is obtained coming from Sarepta Rehabs and Entrada by means of unrestricted grants. H.G. has nothing to reveal in regard to the topics covered within this composition. In the past 5 years, he has actually additionally received consultancy gratuity coming from UCB. M.S. acquired consultancy honoraria coming from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly and also Solaxa in the past 5 years, all unconnected to today document. R.S. possesses absolutely nothing to make known in regard to the subjects covered within this document. She has actually obtained sound speaker and/or consultancy gratuity or even financing additions coming from Abbvie, Bial, STADA as well as Everpharma previously 5 years.